Open Travel Guide
  1. Home
  2. Destinations
  3. Italy
  4. Lazio
  5. Rome
  6. Hotels
  7. Six Senses Rome

Hotels · Lazio, Rome

Six Senses Rome

  • Price$$$$
  • CategoryLuxury
  • Rating★ 4.7

Six Senses Rome occupies a restored 15th-century palazzo on Piazza di San Marcello, a small square just off Via del Corso close to the Trevi Fountain, in Rome's Lazio region. The hotel is built around a well that draws on an ancient Roman aqueduct, and the wellness concept for which Six Senses is known runs throughout the property, from an extensive medical wellness clinic to circadian lighting and locally sourced dining.

A wellness-focused luxury hotel in a restored 15th-century palazzo on Piazza di San Marcello, near the Trevi Fountain, built around an ancient Roman well and offering an extensive biohacking-oriented spa.

Six Senses Rome occupies a restored 15th-century palazzo on Piazza di San Marcello, a small square just off Via del Corso close to the Trevi Fountain, in Rome's Lazio region. The hotel is built around a well that draws on an ancient Roman aqueduct, and the wellness concept for which Six Senses is known runs throughout the property, from an extensive medical wellness clinic to circadian lighting and locally sourced dining.

The hotel offers 96 rooms and suites finished with a restrained material palette of stone, wood and brass, referencing the building's history while introducing contemporary comfort. The subterranean spa includes a biohacking-oriented treatment programme, a vitality pool and an alchemy bar, one of the more extensive wellness offerings among Rome's luxury hotels. Notos, the rooftop restaurant, serves Mediterranean cuisine with views over the surrounding rooftops. Rates for a classic double typically start from around €700 (~$760 USD) in shoulder season.

The Trevi Fountain is a two-minute walk, and the Pantheon, Spanish Steps and Piazza Navona are all reachable on foot within 10–15 minutes.

Practical information for Six Senses Rome · Last updated September 2026
Price $$$$
Address Piazza di San Marcello 4, 00187 Roma

Amenities

  • spa
  • pool
  • restaurant
  • bar
  • wifi
  • fitness centre
  • concierge

Weather through the year in Lazio

JAN 10° FEB 12° MAR 16° APR 20° MAY 24° JUN 27° JUL 28° AUG 22° SEP 17° OCT 12° NOV DEC

Best time Shoulder Worth avoiding

Average daytime temperature in °C. Figures are for Lazio.

Location

Piazza di San Marcello 4, 00187 Roma

41.8977, 12.4813 View on map

Highlights

  • Built around an ancient Roman well fed by a historic aqueduct
  • Extensive wellness clinic and spa with biohacking-oriented treatments
  • Notos rooftop restaurant with views over the historic centre
  • Two-minute walk to the Trevi Fountain
  • 96 rooms and suites in a restored 15th-century palazzo

Tips for visiting

  • Book spa and wellness clinic appointments well in advance — they are in high demand
  • Visit the Trevi Fountain very early morning or late evening to avoid the daytime crowds
  • The rooftop restaurant Notos is a good option for a quieter alternative to Trevi-area tourist restaurants
  • Piazza di San Marcello is a small, easy-to-miss square — confirm the entrance location before arrival
  • The Pantheon is a flat, level walk of around 10 minutes from the hotel

When to visit

The hotel's indoor wellness facilities make it appealing year-round; spring and autumn are ideal for exploring the surrounding centro storico on foot.

Accessibility

The hotel has lift access to guest floors and a step-free entrance from Piazza di San Marcello. Guests with specific mobility requirements should contact the hotel in advance.

Frequently asked questions

How far is Six Senses Rome from the Trevi Fountain?

The Trevi Fountain is approximately a two-minute walk from the hotel.

Does the hotel focus on wellness?

Yes, Six Senses Rome includes an extensive spa and wellness clinic offering treatment programmes, a vitality pool and personalised wellness consultations.

Is there an ancient feature within the hotel?

Yes, the property is built around a well connected to an ancient Roman aqueduct, visible within the building.

Ready to book

Six Senses Rome

Check rates on Booking.com