21c Museum Hotel Nashville at 221 2nd Ave N occupies a historic building in the Printer's Alley area of downtown Nashville, Tennessee, near the intersection of 2nd Avenue and its cluster of 19th-century brick warehouse conversions. The 21c brand operates museum hotels across several southern and midwestern US cities and installs a free contemporary art museum in each property, open 24 hours a day to both hotel guests and the general public, with no admission charge. The Nashville location features rotating exhibitions by emerging and established contemporary artists across multiple gallery floors, making it a meaningful cultural destination independent of its accommodation function. Guest rooms are offered in Urban King, Deluxe Suite, and Collectors Suite categories. Art installations extend from the public galleries into the corridors and guest rooms themselves — visitors sleep surrounded by curated contemporary works that are regularly rotated and refreshed. Rooms feature premium linens, adjustable lighting, and streaming-capable flat-screen TVs, with in-room USB and standard power points placed ergonomically through the space. Husk Nashville, the hotel's signature restaurant, is a James Beard Award-recognized concept that applies a strict regional sourcing philosophy to Southern cooking, restricting the menu exclusively to ingredients grown, raised, or produced in the American South. This commitment makes it one of Nashville's most notable dining destinations regardless of hotel affiliation, and reservations are frequently required well in advance. A lobby bar and lounge serve cocktails and lighter fare throughout the day. A fitness center is available to guests. The Printer's Alley location places the hotel within a short walk of Broadway's entertainment district, Nissan Stadium, and the Tennessee State Capitol grounds.
Room types
- Urban King
- Deluxe Suite
- Collectors Suite
Amenities
- Free contemporary art museum open 24/7
- Husk Nashville restaurant
- Fitness center
- Curated art throughout rooms
- Concierge
Location
221 2nd Ave N, Nashville, TN 37201
36.1649, -86.7762 View on map
Highlights
- Free 24/7 contemporary art museum with rotating exhibitions open to guests and the public
- Husk Nashville restaurant with strict Southern regional sourcing and James Beard recognition
- Art installations extending into guest room corridors and individual room interiors
- Historic building in Printer's Alley, one of Nashville's oldest entertainment corridors
- Central downtown location near Broadway, 2nd Avenue warehouses, and Nissan Stadium
Tips for visiting
- The art museum is free and open 24 hours — exploring exhibitions at midnight is possible and atmospheric
- Make Husk Nashville reservations well in advance; demand frequently exceeds seating availability on weekends
- The hotel's curated art guide, available at the front desk, helps navigate the full collection across floors
- Printer's Alley contains some of Nashville's oldest bars and can be explored on foot from the hotel entrance
- Check the 21c Nashville calendar for art openings and special events during the stay period
Accessibility
21c Museum Hotel Nashville provides ADA-compliant guest rooms with accessible bathrooms and roll-in showers. Elevator access is available to all floors, and the public art museum galleries are wheelchair accessible. Guests requiring mobility accommodations should contact the hotel when booking.
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Frequently asked questions
Is the art museum at 21c Nashville free to enter?
Yes. The contemporary art museum at 21c Museum Hotel Nashville is open to the public 24 hours a day, seven days a week, with no admission charge. Both hotel guests and non-guests are welcome.
What makes Husk Nashville special?
Husk Nashville follows a strict regional sourcing philosophy, using only ingredients grown, raised, or produced within the American South. It is associated with James Beard Award recognition and is regarded as one of Nashville's most committed farm-to-table restaurant concepts.
What type of hotel is 21c Museum Hotel Nashville?
It is an art-forward boutique hotel that integrates a functioning contemporary art museum into its public spaces, corridors, and guest rooms. The 21c brand operates similar properties in other southern and midwestern US cities.
Is 21c Nashville well located for downtown exploration?
The hotel at 221 2nd Ave N in Printer's Alley is within a short walk of Broadway's entertainment district, the Tennessee State Capitol, and Nissan Stadium.
Does 21c Museum Hotel Nashville have a pool or spa?
The hotel does not have an on-site pool or spa. A fitness center is available to guests, and the central location provides walking access to nearby wellness services.