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Hotels · California, San Francisco

The St. Regis San Francisco

  • Price$350-$800
  • CategoryLuxury
  • Rating★ 4.6

The St. Regis San Francisco is a five-star hotel at 125 3rd Street in the SoMa district of San Francisco, California, occupying the upper floors of a tower above the Museum of the African Diaspora. The setting is the city's cultural heart: SFMOMA, Yerba Buena Gardens, the Contemporary Jewish Museum and the Moscone Center are all within a few blocks, Montgomery Street BART and Muni station is a short walk, and Union Square lies roughly ten minutes away on foot.

Five-star hotel above the Museum of the African Diaspora in SoMa, near SFMOMA and Moscone Center.

The St. Regis San Francisco is a five-star hotel at 125 3rd Street in the SoMa district of San Francisco, California, occupying the upper floors of a tower above the Museum of the African Diaspora. The setting is the city's cultural heart: SFMOMA, Yerba Buena Gardens, the Contemporary Jewish Museum and the Moscone Center are all within a few blocks, Montgomery Street BART and Muni station is a short walk, and Union Square lies roughly ten minutes away on foot. The hotel is a contemporary luxury property, aimed at travellers who want the service standards associated with the St. Regis brand in a modern glass tower rather than a historic building. Accommodation consists of Deluxe King rooms and suites, which are generally spacious and are known for their high floors and city views. Amenities listed include a spa, a restaurant, a bar, a fitness centre and free Wi-Fi. The spa is a significant draw for visitors who want wellness facilities within the hotel itself, and the fitness centre and treatment rooms are suited to longer stays and business trips alike. Dining on site includes a restaurant for breakfast and dinner and a bar for cocktails and light meals, and the surrounding SoMa district has a large number of well-regarded restaurants within easy reach. The brand is known for a butler-style service concept, and the staff emphasise personal attention, with a concierge able to arrange restaurant bookings, transport and city excursions. The hotel is popular with executives, convention guests and leisure travellers celebrating special occasions. Nightly rates typically run from about $350 to $800, with the highest prices during major conferences and the autumn season. Visitors should note that the streets around the museum cluster are quieter in the evening than the Union Square district, so late-night walks are best planned along main routes. The property suits guests who want a polished, high-service stay close to museums, the convention centre and downtown transit.

Practical information for The St. Regis San Francisco · Last updated September 2026
Price $350-$800
Address 125 3rd St, San Francisco, CA 94103

Room types

  • Deluxe King
  • Suite

Amenities

  • spa
  • restaurant
  • bar
  • fitness centre
  • free Wi-Fi

Location

125 3rd St, San Francisco, CA 94103

37.7861, -122.4014 View on map

Highlights

  • Five-star tower above the Museum of the African Diaspora
  • Steps from SFMOMA and Yerba Buena Gardens
  • On-site spa, restaurant, bar and fitness centre
  • Walkable to Moscone Center and Montgomery BART

Tips for visiting

  • Request a high floor for the best city views.
  • Book far ahead for large conferences at Moscone Center.
  • Combine a stay with SFMOMA and Yerba Buena Gardens, both within a few blocks.
  • Ask the concierge for restaurant reservations in SoMa.

Accessibility

Modern luxury high-rise hotels typically provide elevator access and accessible rooms; visitors with mobility needs should confirm details directly with the hotel.

Frequently asked questions

Where is The St. Regis San Francisco?

It is at 125 3rd Street in SoMa, above the Museum of the African Diaspora and near SFMOMA.

Does it have a spa?

Yes. A spa is listed among the hotel's amenities, alongside a fitness centre.

What rooms are available?

Deluxe King rooms and suites are offered.

Ready to book

The St. Regis San Francisco

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